بررسی مقایسه‌ای سرولوژی اریون در کودکان مبتلا به کاهش شنوایی حسی عصبی و کودکان غیرمبتلا Comparative Study of Mumps Serology in SNHL Children and Unaffected Ones

    Background & Aim: Mumps infection is endemic in Iran. Due to high percentage of unvaccinated young people(10y(2.1%). Acute mumps infection(positive IgM) was seen in 8.3% and previous immunity to mumps(IgG) in 24.1% of all. The highest incidence of acute infection(IgM) was in 3-5-year old group, but it was not different in other age groups(P=0.11). Previous infection(IgG was also higher in 3-5-year old group and it was significantly different in other age groups(P=0.05). Acute(IgM) and previous infection(IgG), except in mean age of children(P=0.015, 0.013), was not significantly differente in terms of sex in case and control groups(P=1 0.4). Seventy-five percent of all children had no immunity to mumps infection. Twenty-four percent of SNLH patients(like other healthy children) had immunity to mumps infection. Acute mumps infection was seen in 8.8% of 3-5-year-old children of case compared to 6.8% of control group(P=0.11) However, previous immunity in case was lower than control group(P=0.4). Conclusion: Mumps infection in SNLH children aged between 3-5-year-old is more common and important than other age groups. Since the risk of SNHL after mumps infection will increase in older age, prevention of mumps by inexpensive and very effective mumps vaccine is helpful. Thereby, the costs of mumps infection and its sequles can be decreased with massive vaccination of Iranian young people (<20 years old). 3) Mumps Vaccination